MetaCyc Pathway: pyruvate fermentation to butanol II (engineered) in Azospirillum brasilense Sp245

Add experiment(s):


Acetyl-CoA C-acyltransferase:
2 acetyl-CoA→acetoacetyl-CoA + coenzyme A (EC 2.3.1.16; 2.3.1.9)
AZOBR_RS20220
AZOBR_RS28180
AZOBR_RS30610
3-hydroxyacyl-CoA dehydrogenase (in reverse):
acetoacetyl-CoA + NADH + H+→(S)-3-hydroxybutanoyl-CoA + NAD+ (EC 1.1.1.35)
AZOBR_RS09555
AZOBR_RS16920
AZOBR_RS20225
AZOBR_RS26110
AZOBR_RS29225
(S)-3-hydroxybutanoyl-CoA→crotonyl-CoA + H2O (EC 4.2.1.150)
AZOBR_RS01260
AZOBR_RS03680
AZOBR_RS07775
AZOBR_RS09775
AZOBR_RS13325
AZOBR_RS15730
AZOBR_RS18155
AZOBR_RS24105
AZOBR_RS24715
AZOBR_RS26270
AZOBR_RS26485
AZOBR_RS26830
AZOBR_RS27635
AZOBR_RS29210
Trans-2-enoyl-CoA reductase (NAD(+)) (in reverse):
crotonyl-CoA + NADH + H+→butanoyl-CoA + NAD+ (EC 1.3.1.44)
AZOBR_RS09415
AZOBR_RS13155
AZOBR_RS22300
AZOBR_RS22365
AZOBR_RS24750
AZOBR_RS29200
AZOBR_RS31550
Butanal dehydrogenase (in reverse):
butanoyl-CoA + NAD(P)H + H+→1-butanal + coenzyme A + NAD(P)+ (EC 1.2.1.57)
No genes
1-butanal + NADH + H+→butan-1-ol + NAD+
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information