MetaCyc Pathway: superpathway of L-cysteine biosynthesis (fungi) in Azospirillum brasilense Sp245

Add experiment(s):


Homoserine O-acetyltransferase:
L-homoserine + acetyl-CoA→O-acetyl-L-homoserine + coenzyme A (EC 2.3.1.31)
AZOBR_RS14010
AZOBR_RS14580
AZOBR_RS20470
AZOBR_RS20475
O-acetylhomoserine aminocarboxypropyltransferase:
O-acetyl-L-homoserine + hydrogen sulfide→L-homocysteine + acetate + H+ (EC 2.5.1.49)
AZOBR_RS02140
AZOBR_RS07765
AZOBR_RS07770
AZOBR_RS11340
Cystathionine beta-synthase:
L-homocysteine + L-serine→L-cystathionine + H2O (EC 4.2.1.22)
No genes
Cystathionine gamma-lyase:
L-cystathionine + H2O→L-cysteine + 2-oxobutanoate + ammonium (EC 4.4.1.1)
No genes
Cystathionine gamma-synthase:
L-cysteine + O-succinyl-L-homoserine→L-cystathionine + H+ + succinate (EC 2.5.1.48)
AZOBR_RS02140
AZOBR_RS07765
AZOBR_RS07770
AZOBR_RS11340
Cysteine-S-conjugate beta-lyase:
L-cystathionine + H2O→L-homocysteine + ammonium + pyruvate (EC 4.4.1.13)
AZOBR_RS08650

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information