MetaCyc Pathway: dTDP-β-L-rhamnose biosynthesis in Azospirillum brasilense Sp245

Phosphoglucomutase (in reverse):
D-glucopyranose 6-phosphate→α-D-glucopyranose 1-phosphate (EC 5.4.2.2)

Glucose-1-phosphate thymidylyltransferase:
α-D-glucopyranose 1-phosphate + H⁺ + dTTP→dTDP-α-D-glucose + diphosphate (EC 2.7.7.24)

AZOBR_RS33425

dTDP-glucose 4,6-dehydratase:
dTDP-α-D-glucose→dTDP-4-dehydro-6-deoxy-α-D-glucopyranose + H₂O (EC 4.2.1.46)

dTDP-4-dehydrorhamnose 3,5-epimerase:
dTDP-4-dehydro-6-deoxy-α-D-glucopyranose→dTDP-4-dehydro-β-L-rhamnose (EC 5.1.3.13)

AZOBR_RS33410

dTDP-4-dehydrorhamnose reductase (in reverse):
dTDP-4-dehydro-β-L-rhamnose + NADPH + H⁺→dTDP-β-L-rhamnose + NADP⁺ (EC 1.1.1.133)

AZOBR_RS33420

Links:

Pathway details at MetaCyc
Fitness data for 11 genes
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All MetaCyc pathways for Azospirillum brasilense Sp245

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information