MetaCyc Pathway: D-glucarate degradation II in Acidovorax sp. GW101-3H11

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Glucarate dehydratase:
D-glucarate→5-dehydro-4-deoxy-D-glucarate + H2O (EC 4.2.1.40)
Ac3H11_338
5-dehydro-4-deoxyglucarate dehydratase:
5-dehydro-4-deoxy-D-glucarate + H+→2,5-dioxopentanoate + CO2 + H2O (EC 4.2.1.41)
Ac3H11_2339
Ac3H11_336
2,5-dioxovalerate dehydrogenase:
2,5-dioxopentanoate + NADP+ + H2O→2-oxoglutarate + NADPH + 2 H+ (EC 1.2.1.26)
Ac3H11_255
Ac3H11_3961
Ac3H11_612

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information