MetaCyc Pathway: benzoate biosynthesis I (CoA-dependent, β-oxidative) in Acidovorax sp. GW101-3H11

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Phenylalanine ammonia-lyase:
L-phenylalanine→trans-cinnamate + ammonium (EC 4.3.1.24; 4.3.1.25; 5.4.3.10)
No genes
trans-cinnamate + ATP + coenzyme A→(E)-cinnamoyl-CoA + AMP + diphosphate
No genes
Enoyl-CoA hydratase (in reverse):
(E)-cinnamoyl-CoA + H2O→(S)-3-hydroxy-3-phenylpropanoyl-CoA (EC 4.2.1.17)
Ac3H11_100
Ac3H11_1055
Ac3H11_1056
Ac3H11_1914
Ac3H11_1919
Ac3H11_1931
Ac3H11_1940
Ac3H11_2426
Ac3H11_2523
Ac3H11_2719
Ac3H11_2775
Ac3H11_2862
Ac3H11_3085
Ac3H11_3192
Ac3H11_3409
Ac3H11_4006
Ac3H11_4558
Ac3H11_4657
Ac3H11_4989
Ac3H11_963
3-hydroxyacyl-CoA dehydrogenase:
(S)-3-hydroxy-3-phenylpropanoyl-CoA + NAD+→3-oxo-3-phenylpropanoyl-CoA + NADH + H+ (EC 1.1.1.35)
Ac3H11_1056
Ac3H11_1914
Ac3H11_1931
Ac3H11_2523
Ac3H11_2606
Ac3H11_2741
Ac3H11_4075
Acetyl-CoA C-acyltransferase (in reverse):
3-oxo-3-phenylpropanoyl-CoA + coenzyme A→benzoyl-CoA + acetyl-CoA (EC 2.3.1.16)
Ac3H11_178
Ac3H11_1916
Ac3H11_1932
Ac3H11_2303
Ac3H11_2522
Ac3H11_2740
Ac3H11_2769
Ac3H11_2994
Ac3H11_3407
Ac3H11_3408
Ac3H11_3920
benzoyl-CoA + H2O→benzoate + coenzyme A + H+
No genes
Benzoate--CoA ligase:
benzoate + ATP + coenzyme A→benzoyl-CoA + AMP + diphosphate (EC 6.2.1.25)
Ac3H11_3090
benzoyl-CoA + benzyl alcohol→benzyl benzoate + coenzyme A (EC 2.3.1.196)
No genes
benzyl benzoate + H2O→benzoate + benzyl alcohol + H+
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information