MetaCyc Pathway: 4-hydroxybenzoate biosynthesis III (plants) in Acidovorax sp. GW101-3H11

4-coumarate--CoA ligase: 4-coumarate + ATP + coenzyme A→(E)-4-coumaroyl-CoA + AMP + diphosphate (EC 6.2.1.12)

Ac3H11_3410

(E)-4-coumaroyl-CoA + H2O→3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA (EC 4.1.2.61)

Ac3H11_3409

3-hydroxyacyl-CoA dehydrogenase: 3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA + NAD+→3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA + NADH + H+ (EC 1.1.1.35)

Ac3H11_1056

Ac3H11_1914

Ac3H11_1931

Ac3H11_2523

Ac3H11_2606

Ac3H11_2741

Ac3H11_4075

Acetyl-CoA C-acyltransferase (in reverse): 3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA + coenzyme A→4-hydroxybenzoyl-CoA + acetyl-CoA (EC 2.3.1.16)

Ac3H11_178

Ac3H11_1916

Ac3H11_1932

Ac3H11_2303

Ac3H11_2522

Ac3H11_2740

Ac3H11_2769

Ac3H11_2994

Ac3H11_3407

Ac3H11_3408

Ac3H11_3920

4-hydroxybenzoyl-CoA thioesterase: 4-hydroxybenzoyl-CoA + H2O→4-hydroxybenzoate + coenzyme A + H+ (EC 3.1.2.23)

No genes

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information