MetaCyc Pathway: trans-4-hydroxy-L-proline degradation II in Acidovorax sp. GW101-3H11

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4-hydroxyproline epimerase:
trans-4-hydroxy-L-proline→(4R)-4-hydroxy-D-proline (EC 5.1.1.8)
Ac3H11_4170
(4R)-4-hydroxy-D-proline + a reduced two electron carrier + dioxygen→1-pyrroline-4-hydroxy-2-carboxylate + an oxidized electron carrier + H+ + 2 H2O
Ac3H11_4173
1-pyrroline-4-hydroxy-2-carboxylate deaminase:
1-pyrroline-4-hydroxy-2-carboxylate + H+ + H2O→2,5-dioxopentanoate + ammonium (EC 3.5.4.22)
Ac3H11_4168
2,5-dioxovalerate dehydrogenase:
2,5-dioxopentanoate + NADP+ + H2O→2-oxoglutarate + NADPH + 2 H+ (EC 1.2.1.26)
Ac3H11_255
Ac3H11_3961
Ac3H11_612

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information