MetaCyc Pathway: superpathway of sulfur amino acid biosynthesis (Saccharomyces cerevisiae) in Xanthomonas campestris pv. campestris strain 8004

Add experiment(s):


Homoserine O-acetyltransferase:
L-homoserine + acetyl-CoAO-acetyl-L-homoserine + coenzyme A
(EC 2.3.1.31)
Xcc-8004.1594.1
Xcc-8004.2337.1
Sulfate adenylyltransferase:
sulfate + ATP + H+→adenosine 5'-phosphosulfate + diphosphate
(EC 2.7.7.4)
Xcc-8004.1259.1
Xcc-8004.1260.1
Adenylyl-sulfate kinase:
adenosine 5'-phosphosulfate + ATP→3'-phosphoadenylyl-sulfate + ADP + H+
(EC 2.7.1.25)
Xcc-8004.1260.1
Phosphoadenylyl-sulfate reductase (thioredoxin) (in reverse):
3'-phosphoadenylyl-sulfate + a reduced thioredoxin→sulfite + adenosine 3',5'-bisphosphate + an oxidized thioredoxin + 2 H+
(EC 1.8.4.8)
Xcc-8004.1256.1
Sulfite reductase (NADPH) (in reverse):
sulfite + 3 NADPH + 5 H+→hydrogen sulfide + 3 NADP+ + 3 H2O
(EC 1.8.1.2)
Xcc-8004.1257.1
Xcc-8004.1258.1
Xcc-8004.1687.1
Xcc-8004.5022.1
O-acetylhomoserine aminocarboxypropyltransferase:
O-acetyl-L-homoserine + hydrogen sulfide→L-homocysteine + acetate + H+
(EC 2.5.1.49)
Xcc-8004.1385.1
Cystathionine beta-synthase:
L-homocysteine + L-serine→L-cystathionine + H2O
(EC 4.2.1.22)
Xcc-8004.4518.1
Cystathionine gamma-lyase:
L-cystathionine + H2O→L-cysteine + 2-oxobutanoate + ammonium
(EC 4.4.1.1)
Xcc-8004.4517.1
Cystathionine gamma-synthase:
L-cysteine + O-succinyl-L-homoserine→L-cystathionine + H+ + succinate
(EC 2.5.1.48)
Xcc-8004.1385.1
Xcc-8004.1596.1
Cysteine-S-conjugate beta-lyase:
L-cystathionine + H2O→L-homocysteine + ammonium + pyruvate
(EC 4.4.1.13)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information