Toluene dioxygenase:
toluene + NADH + dioxygen + H+→(1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD+ (EC 1.14.12.11) |
| No genes |
Cis-1,2-dihydrobenzene-1,2-diol dehydrogenase:
(1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD+→3-methylcatechol + NADH + H+ (EC 1.3.1.19) |
| No genes |
Catechol 2,3-dioxygenase:
3-methylcatechol + dioxygen→(2Z,4E)-2-hydroxy-6-oxohepta-2,4-dienoate + H+ (EC 1.13.11.2) |
| No genes |
| (2Z,4E)-2-hydroxy-6-oxohepta-2,4-dienoate + H2O→(2Z)-2-hydroxypenta-2,4-dienoate + acetate + H+ (EC 3.7.1.25) |
| No genes |
2-oxopent-4-enoate hydratase (in reverse):
(2Z)-2-hydroxypenta-2,4-dienoate + H2O→(S)-4-hydroxy-2-oxopentanoate (EC 4.2.1.80) |
| Xcc-8004.200.1 |
4-hydroxy-2-oxovalerate aldolase:
(S)-4-hydroxy-2-oxopentanoate→acetaldehyde + pyruvate (EC 4.1.3.39) |
| No genes |
Acetaldehyde dehydrogenase (acetylating):
acetaldehyde + coenzyme A + NAD+→acetyl-CoA + NADH + H+ (EC 1.2.1.10) |
| No genes |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information