MetaCyc Pathway: siroheme biosynthesis in Vibrio cholerae E7946 ATCC 55056

Add experiment(s):


Uroporphyrinogen-III C-methyltransferase:
uroporphyrinogen-III + S-adenosyl-L-methionine→precorrin-1 + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.107)
CSW01_00600
CSW01_12965
Uroporphyrinogen-III C-methyltransferase:
precorrin-1 + S-adenosyl-L-methionine→precorrin-2 + S-adenosyl-L-homocysteine (EC 2.1.1.107)
CSW01_00600
CSW01_12965
Precorrin-2 dehydrogenase:
precorrin-2 + NAD+→sirohydrochlorin + NADH + 2 H+ (EC 1.3.1.76)
CSW01_00600
CSW01_06860
CSW01_12965
Sirohydrochlorin ferrochelatase:
sirohydrochlorin + Fe2+→siroheme + 2 H+ (EC 4.99.1.4)
CSW01_06860

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information