MetaCyc Pathway: glycine betaine degradation I in Vibrio cholerae E7946 ATCC 55056

Add experiment(s):


Betaine--homocysteine S-methyltransferase:
glycine betaine + L-homocysteineN,N-dimethylglycine + L-methionine
(EC 2.1.1.5)
No genes
Dimethylglycine oxidase:
N,N-dimethylglycine + dioxygen + a tetrahydrofolate→sarcosine + hydrogen peroxide + a 5,10-methylenetetrahydrofolate
(EC 1.5.3.10)
No genes
sarcosine + dioxygen + a tetrahydrofolate→glycine + hydrogen peroxide + a 5,10-methylenetetrahydrofolate (EC 1.5.3.24)
No genes
Sarcosine oxidase:
sarcosine + dioxygen + H2O→glycine + formaldehyde + hydrogen peroxide
(EC 1.5.3.1)
No genes
Glycine hydroxymethyltransferase (in reverse):
glycine + a 5,10-methylenetetrahydrofolate + H2O→L-serine + a tetrahydrofolate
(EC 2.1.2.1)
CSW01_04820
CSW01_15340
L-serine ammonia-lyase:
L-serine→2-aminoprop-2-enoate + H2O
(EC 4.3.1.17)
CSW01_06565
CSW01_17535
Tryptophanase:
2-aminoprop-2-enoate→2-iminopropanoate
(spontaneous) (EC 4.1.99.1; 4.1.99.2; 4.3.1.13; 4.3.1.17; 4.3.1.18; 4.3.3.8; 4.4.1.1; 4.4.1.13; 4.4.1.15; 4.4.1.25; 4.4.1.28; 4.4.1.35; 4.5.1.2)
CSW01_06565
CSW01_14805
CSW01_17535
CSW01_18510
2-iminopropanoate + H2O→pyruvate + ammonium (spontaneous) (EC 3.5.99.10; 4.1.99.1; 4.1.99.2; 4.3.1.13; 4.3.1.17; 4.3.1.18; 4.3.3.8; 4.4.1.1; 4.4.1.13; 4.4.1.15; 4.4.1.25; 4.4.1.28; 4.4.1.35; 4.5.1.2)
CSW01_06565
CSW01_12735
CSW01_14805
CSW01_17535
CSW01_18510

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information