Protocatechuate 4,5-dioxygenase:
protocatechuate + dioxygen→4-carboxy-2-hydroxymuconate-6-semialdehyde + H+ (EC 1.13.11.8) |
| No genes |
| 4-carboxy-2-hydroxymuconate-6-semialdehyde→2-hydroxy-4-carboxymuconate semialdehyde hemiacetal (spontaneous) |
| No genes |
| 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal + NADP+→2-pyrone-4,6-dicarboxylate + NADPH + H+ (EC 1.1.1.312) |
| No genes |
2-pyrone-4,6-dicarboxylate lactonase:
2-pyrone-4,6-dicarboxylate + H2O→(1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + H+ (EC 3.1.1.57) |
| No genes |
| (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate→(1E,3E)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate (spontaneous) (EC 5.3.2.8) |
| No genes |
4-oxalmesaconate hydratase (in reverse):
(1E,3E)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate + H2O→2-hydroxy-4-oxobutane-1,2,4-tricarboxylate (EC 4.2.1.83) |
| No genes |
4-hydroxy-4-methyl-2-oxoglutarate aldolase:
2-hydroxy-4-oxobutane-1,2,4-tricarboxylate→oxaloacetate + pyruvate (EC 4.1.3.17) |
| No genes |
Malate dehydrogenase (oxaloacetate-decarboxylating):
oxaloacetate + H+→pyruvate + CO2 (EC 1.1.1.38; 1.1.1.40; 1.1.1.83; 4.1.1.112) |
| CSW01_02940 |
| CSW01_02945 |
| CSW01_02950 |
| CSW01_04095 |
| CSW01_04100 |
| CSW01_04105 |
| CSW01_06015 |
| CSW01_13540 |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information