MetaCyc Pathway: superpathway of L-tyrosine biosynthesis in Pseudomonas syringae pv. syringae B728a

Add experiment(s):


3-deoxy-7-phosphoheptulonate synthase:
D-erythrose 4-phosphate + phosphoenolpyruvate + H2O→3-deoxy-D-arabino-heptulosonate 7-phosphate + phosphate
(EC 2.5.1.54)
Psyr_2073
Psyr_2900
Psyr_3622
3-dehydroquinate synthase:
3-deoxy-D-arabino-heptulosonate 7-phosphate→3-dehydroquinate + phosphate
(EC 4.2.3.4)
Psyr_0409
3-dehydroquinate dehydratase:
3-dehydroquinate→3-dehydroshikimate + H2O
(EC 4.2.1.10)
Psyr_1363
Psyr_1482
Psyr_4399
Shikimate dehydrogenase (in reverse):
3-dehydroshikimate + NADPH + H+→shikimate + NADP+
(EC 1.1.1.25)
Psyr_0025
Psyr_2132
Psyr_2418
Shikimate kinase:
shikimate + ATP→shikimate 3-phosphate + ADP + H+
(EC 2.7.1.71)
Psyr_0408
3-phosphoshikimate 1-carboxyvinyltransferase:
shikimate 3-phosphate + phosphoenolpyruvate→5-enolpyruvoyl-shikimate 3-phosphate + phosphate
(EC 2.5.1.19)
Psyr_0888
Psyr_3644
Chorismate synthase:
5-enolpyruvoyl-shikimate 3-phosphate→chorismate + phosphate
(EC 4.2.3.5)
Psyr_1853
Chorismate mutase:
chorismate→prephenate
(EC 5.4.99.5)
Psyr_3645
Psyr_4818
Prephenate dehydrogenase:
prephenate + NAD+→3-(4-hydroxyphenyl)pyruvate + CO2 + NADH
(EC 1.3.1.12)
Psyr_3644
Aspartate transaminase (in reverse):
3-(4-hydroxyphenyl)pyruvate + L-glutamate→L-tyrosine + 2-oxoglutarate
(EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
Psyr_0117
Psyr_0230
Psyr_1841
Psyr_1973
Psyr_2000
Psyr_2910
Psyr_3087
Psyr_3615
Psyr_4132
Psyr_4325
Psyr_4898
Psyr_5056

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information