MetaCyc Pathway: L-phenylalanine degradation IV (mammalian, via side chain) in Pseudomonas syringae pv. syringae B728a

Add experiment(s):


Aromatic-L-amino-acid decarboxylase:
L-phenylalanine + H+→2-phenylethylamine + CO2
(EC 4.1.1.28; 4.1.1.53)
No genes
Aspartate transaminase:
L-phenylalanine + 2-oxoglutarate→3-phenyl-2-oxopropanoate + L-glutamate
(EC 2.6.1.1; 2.6.1.27; 2.6.1.57)
Psyr_0117
Psyr_0230
Psyr_1841
Psyr_1973
Psyr_2000
Psyr_2910
Psyr_3087
Psyr_3615
Psyr_4132
Psyr_4325
Psyr_4898
Psyr_5056
4-hydroxyphenylpyruvate dioxygenase:
3-phenyl-2-oxopropanoate + dioxygen→(2-hydroxyphenyl)acetate + CO2
(EC 1.13.11.27)
Psyr_2130
Psyr_3330
Indolelactate dehydrogenase (in reverse):
3-phenyl-2-oxopropanoate + NADH + H+→(R)-3-(phenyl)lactate + NAD+
(EC 1.1.1.110)
No genes
Primary-amine oxidase:
2-phenylethylamine + dioxygen + H2O→phenylacetaldehyde + ammonium + hydrogen peroxide
(EC 1.4.3.21; 1.4.3.4)
Psyr_0455
Psyr_2888
Phenylacetaldehyde dehydrogenase:
phenylacetaldehyde + NAD+ + H2O→phenylacetate + NADH + 2 H+
(EC 1.2.1.39)
Psyr_0629
Phenylacetate--CoA ligase:
phenylacetate + ATP + coenzyme A→phenylacetyl-CoA + AMP + diphosphate
(EC 6.2.1.30)
No genes
Glutamine N-phenylacetyltransferase:
phenylacetyl-CoA + L-glutamine→α-N-phenylacetyl-L-glutamine + coenzyme A + H+
(EC 2.3.1.14)
No genes
phenylacetyl-CoA + glycine→phenylacetylglycine + coenzyme A + H+ (EC 2.3.1.192)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information