MetaCyc Pathway: L-arginine biosynthesis II (acetyl cycle) in Synechocystis sp000284455 PCC 6803

Glutamate--ammonia ligase: L-glutamate + ammonium + ATP→L-glutamine + ADP + H+ + phosphate (EC 6.3.1.2)

SGL_RS04340

SGL_RS11925

Amino-acid N-acetyltransferase: L-glutamate + acetyl-CoA→N-acetyl-L-glutamate + coenzyme A + H+ (EC 2.3.1.1)

SGL_RS10330

Acetylglutamate kinase: N-acetyl-L-glutamate + ATP→N-acetylglutamyl-phosphate + ADP (EC 2.7.2.8)

SGL_RS05885

Carbamoyl-phosphate synthase (glutamine-hydrolyzing): L-glutamine + 2 ATP + hydrogen carbonate + H2O→L-glutamate + carbamoyl phosphate + 2 ADP + 2 H+ + phosphate (EC 6.3.5.5)

SGL_RS03590

SGL_RS14530

SGL_RS17390

N-acetyl-gamma-glutamyl-phosphate reductase (in reverse): N-acetylglutamyl-phosphate + NADPH + H+→N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate (EC 1.2.1.38)

SGL_RS15325

Ornithine carbamoyltransferase: carbamoyl phosphate + L-ornithine→L-citrulline + H+ + phosphate (EC 2.1.3.3)

SGL_RS16800

Acetylornithine transaminase (in reverse): N-acetyl-L-glutamate 5-semialdehyde + L-glutamate→N-acetyl-L-ornithine + 2-oxoglutarate (EC 2.6.1.11)

SGL_RS04875

Argininosuccinate synthase: L-citrulline + ATP + L-aspartate→L-arginino-succinate + AMP + diphosphate + H+ (EC 6.3.4.5)

SGL_RS18195

Argininosuccinate lyase: L-arginino-succinate→L-arginine + fumarate (EC 4.3.2.1)

SGL_RS05520

Glutamate N-acetyltransferase: L-glutamate + N-acetyl-L-ornithine→N-acetyl-L-glutamate + L-ornithine (EC 2.3.1.35)

SGL_RS10330

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information