MetaCyc Pathway: ureide biosynthesis in Sinorhizobium meliloti 1021

IMP dehydrogenase: IMP + NAD+ + H2O→XMP + NADH + H+ (EC 1.1.1.205)

SMa0636

SMa1086

SMa1521

SMc00815

5'-nucleotidase: XMP + H2O→xanthosine + phosphate (EC 3.1.3.5)

SMc01730

SMc02063

SMc04018

Purine-nucleoside phosphorylase: xanthosine + phosphate→xanthine + α-D-ribose-1-phosphate (EC 2.4.2.1)

SMc00850

SMc04123

Xanthine dehydrogenase: xanthine + NAD+ + H2O→urate + NADH + H+ (EC 1.17.1.4)

SM_b20132

SM_b20396

SM_b20846

SM_b21011

SM_b21286

SM_b21287

SM_b21338

SM_b21556

SM_b21557

SMa2037

SMa2041

SMa2351

SMa2353

SMa5011

Urate oxidase: urate + dioxygen + H2O→(S)-5-hydroxyisourate + hydrogen peroxide (EC 1.7.3.3)

SM_b20875

SM_b21284

Hydroxyisourate hydrolase: (S)-5-hydroxyisourate + H2O→(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+ (EC 3.5.2.17)

SM_b20872

SM_b21285

(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+→(S)-(+)-allantoin + CO2 (EC 4.1.1.97)

No genes

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information