MetaCyc Pathway: L-tyrosine biosynthesis I in Sinorhizobium meliloti 1021

MetaCyc Pathway: L-tyrosine biosynthesis I in Sinorhizobium meliloti 1021

Chorismate mutase:
chorismate→prephenate (EC 5.4.99.5)

Prephenate dehydrogenase:
prephenate + NAD⁺→3-(4-hydroxyphenyl)pyruvate + CO₂ + NADH (EC 1.3.1.12)

Aspartate transaminase (in reverse):
3-(4-hydroxyphenyl)pyruvate + L-glutamate→L-tyrosine + 2-oxoglutarate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)

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Pathway details at MetaCyc
Fitness data for 18 genes
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All MetaCyc pathways for Sinorhizobium meliloti 1021

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information