MetaCyc Pathway: L-tyrosine degradation III in Sinorhizobium meliloti 1021

MetaCyc Pathway: L-tyrosine degradation III in Sinorhizobium meliloti 1021

Phenylalanine(histidine) transaminase:
L-tyrosine + pyruvate→3-(4-hydroxyphenyl)pyruvate + L-alanine (EC 2.6.1.58)

No genes

Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)

4-hydroxyphenylpyruvate decarboxylase:
3-(4-hydroxyphenyl)pyruvate + H⁺→(4-hydroxyphenyl)acetaldehyde + CO₂ (EC 4.1.1.80)

No genes

Alcohol dehydrogenase (in reverse):
(4-hydroxyphenyl)acetaldehyde + NADH + H⁺→4-tyrosol + NAD⁺ (EC 1.1.1.1)

Links:

Pathway details at MetaCyc
Fitness data for 28 genes
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All MetaCyc pathways for Sinorhizobium meliloti 1021

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information