MetaCyc Pathway: succinoglycan biosynthesis in Sinorhizobium meliloti 1021

Undecaprenyl-phosphate galactose phosphotransferase: UDP-α-D-galactose + di-trans,octa-cis-undecaprenyl phosphate→α-D-Gal-PP-Und + UMP (EC 2.7.8.6)

SM_b20946

SM_b21071

α-D-Gal-PP-Und + UDP-α-D-glucose→β-D-Glc-(1→3)-α-D-Gal-PP-Und + H+ + UDP

SM_b20957

β-D-Glc-(1→3)-α-D-Gal-PP-Und + UDP-α-D-glucose→β-D-Glc-(1→4)-β-D-Glc-(1→3)-α-D-Gal-diphosphoundecaprenol + H+ + UDP

SM_b20956

β-D-Glc-(1→4)-β-D-Glc-(1→3)-α-D-Gal-diphosphoundecaprenol + acetyl-CoA→6-O-acetyl-β-D-Glc-(1→4)-β-D-Glc-(1→3)-α-D-Gal-PP-Und + coenzyme A

SM_b20943

6-O-acetyl-β-D-Glc-(1→4)-β-D-Glc-(1→3)-α-D-Gal-PP-Und + UDP-α-D-glucose→D-Glc-(1→4)-6-O-acetyl-β-D-Glc-(1→4)-β-D-Glc-(1→3)-α-D-Gal-PP-Und + H+ + UDP

SM_b20958

D-Glc-(1→4)-6-O-acetyl-β-D-Glc-(1→4)-β-D-Glc-(1→3)-α-D-Gal-PP-Und + UDP-α-D-glucose→β-D-Glc-(1→6)-β-D-Glc-(1→4)-6-O-acetyl-β-D-Glc-(1→4)-β-D-Glc-(1→3)-α-D-Gal-diphosphoundecaprenol + H+ + UDP

SM_b20959

β-D-Glc-(1→6)-β-D-Glc-(1→4)-6-O-acetyl-β-D-Glc-(1→4)-β-D-Glc-(1→3)-α-D-Gal-diphosphoundecaprenol + UDP-α-D-glucose→β-D-Glc-(1→6)-β-D-Glc-(1→6)-β-D-Glc-(1→4)-6-O-acetyl-β-D-Glc-(1→4)-β-D-Glc-(1→3)-α-D-Gal-PP-Und + H+ + UDP

SM_b20948

β-D-Glc-(1→6)-β-D-Glc-(1→6)-β-D-Glc-(1→4)-6-O-acetyl-β-D-Glc-(1→4)-β-D-Glc-(1→3)-α-D-Gal-PP-Und + UDP-α-D-glucose→β-D-Glc-(1→3)-β-D-Glc-(1→6)-β-D-Glc-(1→6)-β-D-Glc-(1→4)-6-O-acetyl-β-D-Glc-(1→4)-β-D-Glc-(1→3)-α-D-Gal-PP-Und + H+ + UDP

SM_b21690

β-D-Glc-(1→3)-β-D-Glc-(1→6)-β-D-Glc-(1→6)-β-D-Glc-(1→4)-6-O-acetyl-β-D-Glc-(1→4)-β-D-Glc-(1→3)-α-D-Gal-PP-Und + succinyl-CoA→6-O-succinoyl-β-D-Glc-(1→3)-β-D-Glc-(1→6)-β-D-Glc-(1→6)-β-D-Glc-(1→4)-6-O-acetyl-β-D-Glc-(1→4)-β-D-Glc-(1→3)-α-D-Gal-PP-Und + coenzyme A

SM_b20954

6-O-succinoyl-β-D-Glc-(1→3)-β-D-Glc-(1→6)-β-D-Glc-(1→6)-β-D-Glc-(1→4)-6-O-acetyl-β-D-Glc-(1→4)-β-D-Glc-(1→3)-α-D-Gal-PP-Und + UDP-α-D-glucose→β-D-Glc-(1→3)-6-O-succinoyl-β-D-Glc-(1→3)-β-D-Glc-(1→6)-β-D-Glc-(1→6)-β-D-Glc-(1→4)-6-O-acetyl-β-D-Glc-(1→4)-β-D-Glc-(1→3)-α-D-Gal-PP-Und + H+ + UDP

No genes

β-D-Glc-(1→3)-6-O-succinoyl-β-D-Glc-(1→3)-β-D-Glc-(1→6)-β-D-Glc-(1→6)-β-D-Glc-(1→4)-6-O-acetyl-β-D-Glc-(1→4)-β-D-Glc-(1→3)-α-D-Gal-PP-Und + phosphoenolpyruvate→4,6-pyruvoyl-β-D-Glc-(1→3)-6-O-succinoyl-β-D-Glc-(1→3)-β-D-Glc-(1→6)-β-D-Glc-(1→6)-β-D-Glc-(1→4)-6-O-acetyl-β-D-Glc-(1→4)-β-D-Glc-(1→3)-α-D-Gal-PP-Und + phosphate

SM_b20949

4,6-pyruvoyl-β-D-Glc-(1→3)-6-O-succinoyl-β-D-Glc-(1→3)-β-D-Glc-(1→6)-β-D-Glc-(1→6)-β-D-Glc-(1→4)-6-O-acetyl-β-D-Glc-(1→4)-β-D-Glc-(1→3)-α-D-Gal-PP-Und[in] + H+[out]→4,6-pyruvoyl-β-D-Glc-(1→3)-6-O-succinoyl-β-D-Glc-(1→3)-β-D-Glc-(1→6)-β-D-Glc-(1→6)-β-D-Glc-(1→4)-6-O-acetyl-β-D-Glc-(1→4)-β-D-Glc-(1→3)-α-D-Gal-PP-Und[out] + H+[in]

SM_b20950

n 4,6-pyruvoyl-β-D-Glc-(1→3)-6-O-succinoyl-β-D-Glc-(1→3)-β-D-Glc-(1→6)-β-D-Glc-(1→6)-β-D-Glc-(1→4)-6-O-acetyl-β-D-Glc-(1→4)-β-D-Glc-(1→3)-α-D-Gal-PP-Und→succinoglycan + n-1 H+ + n-1 di-trans,octa-cis-undecaprenyl diphosphate (EC 2.4.99.26)

SM_b20944

2 4,6-pyruvoyl-β-D-Glc-(1→3)-6-O-succinoyl-β-D-Glc-(1→3)-β-D-Glc-(1→6)-β-D-Glc-(1→6)-β-D-Glc-(1→4)-6-O-acetyl-β-D-Glc-(1→4)-β-D-Glc-(1→3)-α-D-Gal-PP-Und→succinoglycan dimer + H+ + di-trans,octa-cis-undecaprenyl diphosphate

SM_b20961

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information