MetaCyc Pathway: isopenicillin N biosynthesis in Shewanella amazonensis SB2B

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N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase:
L-2-aminoadipate + L-cysteine + L-valine + 3 ATP + H2O→N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + 3 AMP + 3 diphosphate + 3 H+ (EC 6.3.2.26)
No genes
Isopenicillin-N synthase:
N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + dioxygen→isopenicillin N + 2 H2O (EC 1.21.3.1)
Sama_1992

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information