MetaCyc Pathway: inosine-5'-phosphate biosynthesis II in Rhodospirillum rubrum S1H

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Phosphoribosylaminoimidazole carboxylase (in reverse):
5-amino-1-(5-phospho-β-D-ribosyl)imidazole + CO2→5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + 2 H+ (EC 4.1.1.21)
Rru_A1050
Rru_A1051
Phosphoribosylaminoimidazolesuccinocarboxamide synthase:
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + ATP + L-aspartate→5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole + ADP + H+ + phosphate (EC 6.3.2.6)
Rru_A0711
Adenylosuccinate lyase:
5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole→5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + fumarate (EC 4.3.2.2)
Rru_A0716
Rru_A1963
Phosphoribosylaminoimidazolecarboxamide formyltransferase:
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + an N10-formyltetrahydrofolate→5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide + a tetrahydrofolate (EC 2.1.2.3)
Rru_A3655
IMP cyclohydrolase (in reverse):
5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide→IMP + H2O (EC 3.5.4.10)
Rru_A3655

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information