MetaCyc Pathway: L-tyrosine degradation I in Ralstonia solanacearum IBSBF1503

Add experiment(s):


Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
RALBFv3_RS02730
RALBFv3_RS06840
RALBFv3_RS07975
RALBFv3_RS10325
RALBFv3_RS12310
RALBFv3_RS12800
RALBFv3_RS13765
RALBFv3_RS14115
RALBFv3_RS14220
RALBFv3_RS15870
RALBFv3_RS17935
RALBFv3_RS18715
RALBFv3_RS19940
4-hydroxyphenylpyruvate dioxygenase:
3-(4-hydroxyphenyl)pyruvate + dioxygen→homogentisate + CO2 (EC 1.13.11.27)
RALBFv3_RS07685
RALBFv3_RS16960
RALBFv3_RS17435
Homogentisate 1,2-dioxygenase:
homogentisate + dioxygen→4-maleyl-acetoacetate + H+ (EC 1.13.11.5)
RALBFv3_RS20240
Maleylacetoacetate isomerase:
4-maleyl-acetoacetate→4-fumaryl-acetoacetate (EC 5.2.1.2)
RALBFv3_RS11050
RALBFv3_RS14610
Fumarylacetoacetase:
4-fumaryl-acetoacetate + H2O→acetoacetate + fumarate + H+ (EC 3.7.1.2)
RALBFv3_RS11045
RALBFv3_RS14615
RALBFv3_RS20245

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information