MetaCyc Pathway: L-citrulline biosynthesis in Ralstonia solanacearum IBSBF1503

Add experiment(s):


Arginase:
L-arginine + H2O→L-ornithine + urea (EC 3.5.3.1)
RALBFv3_RS10165
RALBFv3_RS17310
Glutamate synthase (NADPH):
L-glutamine + H2O→L-glutamate + ammonia + H+ (EC 1.4.1.13; 1.4.1.14; 1.4.7.1; 2.6.1.85; 3.5.1.2; 3.5.1.38; 4.1.3.27; 4.3.2.10; 4.3.3.6; 6.3.4.2; 6.3.5.13; 6.3.5.2; 6.3.5.4; 6.3.5.5; 6.3.5.6; 6.3.5.7)
RALBFv3_RS00525
RALBFv3_RS02190
RALBFv3_RS02200
RALBFv3_RS05330
RALBFv3_RS05730
RALBFv3_RS06485
RALBFv3_RS06490
RALBFv3_RS06910
RALBFv3_RS06915
RALBFv3_RS08690
RALBFv3_RS09685
RALBFv3_RS09700
RALBFv3_RS09705
RALBFv3_RS12255
RALBFv3_RS14795
RALBFv3_RS14955
RALBFv3_RS18315
RALBFv3_RS18805
L-proline[in] + an electron-transfer quinone→(S)-1-pyrroline-5-carboxylate[in] + an electron-transfer quinol + H+[in] (EC 1.5.5.2)
RALBFv3_RS08725
Glutamate 5-kinase:
L-glutamate + ATP→γ-L-glutamyl 5-phosphate + ADP (EC 2.7.2.11)
RALBFv3_RS06145
(S)-1-pyrroline-5-carboxylate + H+ + H2O→L-glutamate 5-semialdehyde (spontaneous)
No genes
Glutamate-5-semialdehyde dehydrogenase (in reverse):
γ-L-glutamyl 5-phosphate + NADPH + H+→L-glutamate 5-semialdehyde + NADP+ + phosphate (EC 1.2.1.41)
RALBFv3_RS05825
Ornithine aminotransferase (in reverse):
L-glutamate + L-glutamate 5-semialdehyde→L-ornithine + 2-oxoglutarate (EC 2.6.1.13)
RALBFv3_RS10170
Ornithine carbamoyltransferase:
L-ornithine + carbamoyl phosphate→L-citrulline + H+ + phosphate (EC 2.1.3.3)
RALBFv3_RS05185

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information