MetaCyc Pathway: dermatan sulfate degradation I (bacterial) in Rahnella sp. WP5

Add experiment(s):


Chondroitin B lyase:
dermatan sulfate containing 4-O-sulfo-N-acetyl-D-galactosamine and L-iduronate 2-O-sulfate-[core protein]→n 4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate (EC 4.2.2.19; 4.2.2.20)
No genes
Chondroitin-sulfate-ABC exolyase:
dermatan sulfate containing 4-O-sulfo-N-acetyl-D-galactosamine and L-iduronate 2-O-sulfate-[core protein]→4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate + dermatan sulfate containing 4-O-sulfo-N-acetyl-D-galactosamine and L-iduronate 2-O-sulfate-[core protein] (EC 4.2.2.21)
No genes
Chondro-4-sulfatase:
4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate + H2O→4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine + H+ + sulfate (EC 3.1.6.9)
No genes
4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine + H2O→4-deoxy-L-threo-hex-4-enopyranuronate + N-acetyl-D-galactosamine (EC 3.2.1.179)
EX31_RS10915

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information