MetaCyc Pathway: guanosine ribonucleotides de novo biosynthesis in Rahnella sp. WP5

Add experiment(s):


IMP dehydrogenase:
IMP + NAD+ + H2O→XMP + NADH + H+ (EC 1.1.1.205)
EX31_RS20450
GMP synthase (glutamine-hydrolyzing):
XMP + ATP + L-glutamine + H2O→GMP + AMP + L-glutamate + diphosphate + 2 H+ (EC 6.3.5.2)
EX31_RS08365
EX31_RS20445
Guanylate kinase:
GMP + ATP→GDP + ADP (EC 2.7.4.8)
EX31_RS08445
EX31_RS15800
Nucleoside-diphosphate kinase:
GDP + ATP→GTP + ADP (EC 2.7.4.6)
EX31_RS20530
EX31_RS22535

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information