MetaCyc Pathway: L-glutamate degradation V (via hydroxyglutarate) in Rhodopseudomonas palustris CGA009

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Glutamate dehydrogenase:
L-glutamate + NAD+ + H2O→2-oxoglutarate + ammonium + NADH + H+ (EC 1.4.1.2)
No genes
2-oxoglutarate + NADH + H+→(R)-2-hydroxyglutarate + NAD+ (EC 1.1.1.399)
No genes
Glutaconate CoA-transferase:
(R)-2-hydroxyglutarate + acetyl-CoA→(R)-2-hydroxyglutaryl-CoA + acetate (EC 2.8.3.12)
TX73_005290
TX73_005295
TX73_011980
TX73_011985
TX73_024150
TX73_024155
(R)-2-hydroxyglutaryl-CoA→(E)-glutaconyl-CoA + H2O (EC 4.2.1.167)
No genes
(E)-glutaconyl-CoA[in] + Na+[in] + H+[in]→crotonyl-CoA[in] + CO2[in] + Na+[out] (EC 7.2.4.5)
No genes
crotonyl-CoA + H2O→(S)-3-hydroxybutanoyl-CoA (EC 4.2.1.150)
TX73_001990
TX73_002165
TX73_002395
TX73_002500
TX73_002510
TX73_003370
TX73_004930
TX73_006355
TX73_007240
TX73_008810
TX73_009040
TX73_009055
TX73_009185
TX73_009315
TX73_011975
TX73_014325
TX73_017085
TX73_019255
TX73_019650
TX73_022390
TX73_022490
crotonyl-CoA[cytosol] + 2 NADH[cytosol] + 2 an oxidized ferredoxin [iron-sulfur] cluster[cytosol]→butanoyl-CoA[cytosol] + 2 NAD+[cytosol] + 2 a reduced ferredoxin [iron-sulfur] cluster[cytosol] (EC 1.3.1.109)
No genes
Propionate CoA-transferase:
butanoyl-CoA + acetate→acetyl-CoA + butanoate (EC 2.8.3.1; 2.8.3.8)
No genes
3-hydroxyacyl-CoA dehydrogenase:
(S)-3-hydroxybutanoyl-CoA + NAD+→acetoacetyl-CoA + NADH + H+ (EC 1.1.1.35)
TX73_004220
TX73_008775
TX73_011910
TX73_018155
TX73_019255
TX73_024670
Acetyl-CoA C-acyltransferase (in reverse):
acetoacetyl-CoA + coenzyme A→2 acetyl-CoA (EC 2.3.1.16; 2.3.1.9)
TX73_002660
TX73_002750
TX73_004215
TX73_008765
TX73_009030
TX73_011915
TX73_016520
TX73_017920
TX73_017940
TX73_019245
TX73_022530

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information