MetaCyc Pathway: gondoate biosynthesis (anaerobic) in Pseudomonas fluorescens SBW25-INTG

Add experiment(s):


Beta-ketoacyl-acyl-carrier-protein synthase II:
an oleoyl-[acp] + a malonyl-[acp] + H+→an (11Z)-3-oxo-icos-11-enoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
PFLU_RS02075
PFLU_RS02090
PFLU_RS09030
PFLU_RS15160
PFLU_RS15590
PFLU_RS23045
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
an (11Z)-3-oxo-icos-11-enoyl-[acp][cytosol] + NADPH[cytosol] + H+[cytosol]→a (3R,11Z)-3-hydroxy-icos-11-enoyl-[acp][cytosol] + NADP+[cytosol] (EC 1.1.1.100)
PFLU_RS02080
PFLU_RS03220
PFLU_RS05335
PFLU_RS05340
PFLU_RS09615
PFLU_RS09635
PFLU_RS09805
PFLU_RS09810
PFLU_RS12555
PFLU_RS14865
PFLU_RS14960
PFLU_RS15050
PFLU_RS15565
PFLU_RS15990
PFLU_RS16275
PFLU_RS17200
PFLU_RS18190
PFLU_RS19495
PFLU_RS22760
PFLU_RS22960
PFLU_RS23055
PFLU_RS30525
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R,11Z)-3-hydroxy-icos-11-enoyl-[acp][cytosol]→a (2E,11Z)-icosa-2,11-dienoyl-[acp][cytosol] + H2O[cytosol] (EC 4.2.1.59)
PFLU_RS06330
PFLU_RS09035
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E,11Z)-icosa-2,11-dienoyl-[acp][cytosol] + NADH[cytosol] + H+[cytosol]→a gondoyl-[acp][cytosol] + NAD+[cytosol] (EC 1.3.1.9)
PFLU_RS14490

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information