MetaCyc Pathway: pyrimidine deoxyribonucleotides biosynthesis from CTP in Pseudomonas fluorescens SBW25-INTG

Add experiment(s):


Nucleoside-triphosphatase:
CTP + H2O→CDP + H+ + phosphate (EC 3.6.1.15; 3.6.1.5)
PFLU_RS28400
Ribonucleoside-diphosphate reductase (in reverse):
CDP + a reduced thioredoxin→dCDP + an oxidized thioredoxin + H2O (EC 1.17.4.1)
PFLU_RS13580
PFLU_RS23155
PFLU_RS23365
Nucleoside-diphosphate kinase:
dCDP + ATP→dCTP + ADP (EC 2.7.4.6)
PFLU_RS06135
PFLU_RS24820
Apyrase:
dCDP + H2O→dCMP + H+ + phosphate (EC 3.6.1.5; 3.6.1.6)
No genes
dCMP deaminase:
dCMP + H+ + H2O→dUMP + ammonium (EC 3.5.4.12)
No genes
Thymidylate synthase:
dUMP + a 5,10-methylenetetrahydrofolate→dTMP + a 7,8-dihydrofolate (EC 2.1.1.45)
PFLU_RS28625
T(2)-induced deoxynucleotide kinase:
dTMP + ATP→dTDP + ADP (EC 2.7.4.12; 2.7.4.13; 2.7.4.9)
PFLU_RS23030
Nucleoside-diphosphate kinase:
dTDP + ATP→dTTP + ADP (EC 2.7.4.6)
PFLU_RS06135
PFLU_RS24820

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information