MetaCyc Pathway: coenzyme M biosynthesis II in Parabacteroides merdae CL09T00C40

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O-phospho-L-serine + H+ + sulfite→L-cysteate + phosphate (EC 2.5.1.76)
No genes
Aspartate transaminase:
L-cysteate + 2-oxoglutarate→3-sulfopyruvate + L-glutamate (EC 2.6.1.1)
HMPREF1078_RS01130
HMPREF1078_RS03550
HMPREF1078_RS07595
HMPREF1078_RS12080
HMPREF1078_RS13530
HMPREF1078_RS17495
Sulfopyruvate decarboxylase:
3-sulfopyruvate + H+→sulfoacetaldehyde + CO2 (EC 4.1.1.79)
No genes
sulfoacetaldehyde + L-cysteine→2-(sulfomethyl)thiazolidine-4-carboxylate + H+ + H2O
No genes
2-(sulfomethyl)thiazolidine-4-carboxylate + a reduced two electron carrier + H+→sulfoethylcysteine + an oxidized electron carrier
No genes
sulfoethylcysteine + H2O→coenzyme M + ammonium + pyruvate
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information