MetaCyc Pathway: adipate biosynthesis in Phaeobacter inhibens DSM 17395

Add experiment(s):


3-oxoadipyl-CoA thiolase:
acetyl-CoA + succinyl-CoA→3-oxoadipoyl-CoA + coenzyme A (EC 2.3.1.174)
PGA1_c04090
3-hydroxyacyl-CoA dehydrogenase (in reverse):
3-oxoadipoyl-CoA + NADH + H+→(3S)-hydroxyadipyl-CoA + NAD+ (EC 1.1.1.35)
PGA1_c11320
PGA1_c12020
PGA1_c22740
PGA1_c04110
PGA1_c08420
Enoyl-CoA hydratase:
(3S)-hydroxyadipyl-CoA→(2E)-5-carboxy-2-pentenoyl-CoA + H2O (EC 4.2.1.17)
PGA1_c12020
PGA1_c14440
PGA1_c15660
PGA1_c16990
PGA1_c17350
PGA1_c22740
PGA1_c23460
PGA1_c23920
PGA1_c26820
PGA1_c33450
PGA1_c34200
PGA1_c36500
PGA1_262p01540
PGA1_262p01850
PGA1_262p01980
PGA1_c04110
(2E)-5-carboxy-2-pentenoyl-CoA + FADH2→adipoyl-CoA + FAD + H+
No genes
Succinate--CoA ligase (ADP-forming) (in reverse):
adipoyl-CoA + ADP + phosphate→adipate + ATP + coenzyme A (EC 6.2.1.5)
PGA1_c03610
PGA1_c03630

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information