MetaCyc Pathway: 2-methyl-branched fatty acid β-oxidation in Phaeobacter inhibens DSM 17395

Add experiment(s):


Butyrate--CoA ligase:
a short-chain 2-methyl-branched fatty acid + ATP + coenzyme A→a short-chain 2-methyl fatty acyl-CoA + AMP + diphosphate (EC 6.2.1.2)
No genes
a long-chain 2-methyl fatty acyl-CoA + an oxidized electron-transfer flavoprotein + H+→a long-chain (2E)-2-methyl-2-enoyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.8)
No genes
Butyrate--CoA ligase:
a medium-chain 2-methyl-branched fatty acid + ATP + coenzyme A→a medium-chain 2-methyl fatty acyl-CoA + AMP + diphosphate (EC 6.2.1.2)
No genes
a short-chain 2-methyl fatty acyl-CoA + an oxidized electron-transfer flavoprotein + H+→a short-chain (2E)-2-methyl-2-enoyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.5)
No genes
a medium-chain 2-methyl fatty acyl-CoA + an oxidized electron-transfer flavoprotein + H+→a medium-chain (2E)-2-methyl-2-enoyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.7)
PGA1_c12080
PGA1_c23450
PGA1_c05590
Enoyl-CoA hydratase (in reverse):
a long-chain (2E)-2-methyl-2-enoyl-CoA + H2O→a long-chain (3S)-3-hydroxy-2-methylacyl-CoA (EC 4.2.1.17)
PGA1_c12020
PGA1_c14440
PGA1_c15660
PGA1_c16990
PGA1_c17350
PGA1_c22740
PGA1_c23460
PGA1_c23920
PGA1_c26820
PGA1_c33450
PGA1_c34200
PGA1_c36500
PGA1_262p01540
PGA1_262p01850
PGA1_262p01980
PGA1_c04110
Enoyl-CoA hydratase (in reverse):
a short-chain (2E)-2-methyl-2-enoyl-CoA + H2O→a short-chain (3S)-3-hydroxy-2-methylacyl-CoA (EC 4.2.1.17)
PGA1_c12020
PGA1_c14440
PGA1_c15660
PGA1_c16990
PGA1_c17350
PGA1_c22740
PGA1_c23460
PGA1_c23920
PGA1_c26820
PGA1_c33450
PGA1_c34200
PGA1_c36500
PGA1_262p01540
PGA1_262p01850
PGA1_262p01980
PGA1_c04110
Enoyl-CoA hydratase (in reverse):
a medium-chain (2E)-2-methyl-2-enoyl-CoA + H2O→a medium-chain (3S)-3-hydroxy-2-methylacyl-CoA (EC 4.2.1.17)
PGA1_c12020
PGA1_c14440
PGA1_c15660
PGA1_c16990
PGA1_c17350
PGA1_c22740
PGA1_c23460
PGA1_c23920
PGA1_c26820
PGA1_c33450
PGA1_c34200
PGA1_c36500
PGA1_262p01540
PGA1_262p01850
PGA1_262p01980
PGA1_c04110
3-hydroxyacyl-CoA dehydrogenase:
a long-chain (3S)-3-hydroxy-2-methylacyl-CoA + NAD+→a long-chain 2-methyl-3-oxoacyl-CoA + NADH + H+ (EC 1.1.1.35)
PGA1_c11320
PGA1_c12020
PGA1_c22740
PGA1_c04110
PGA1_c08420
3-hydroxy-2-methylbutyryl-CoA dehydrogenase:
a short-chain (3S)-3-hydroxy-2-methylacyl-CoA + NAD+→a short-chain 2-methyl-3-oxoacyl-CoA + NADH + H+ (EC 1.1.1.178)
PGA1_c11320
3-hydroxyacyl-CoA dehydrogenase:
a medium-chain (3S)-3-hydroxy-2-methylacyl-CoA + NAD+→a medium-chain 2-methyl-3-oxoacyl-CoA + NADH + H+ (EC 1.1.1.35)
PGA1_c11320
PGA1_c12020
PGA1_c22740
PGA1_c04110
PGA1_c08420
Acetyl-CoA C-acyltransferase (in reverse):
a long-chain 2-methyl-3-oxoacyl-CoA + coenzyme A→a long-chain 2-methyl fatty acyl-CoA + propanoyl-CoA (EC 2.3.1.16)
PGA1_c12030
PGA1_c22730
PGA1_c33180
PGA1_c03400
PGA1_c34350
PGA1_c04090
PGA1_c04120
Acetyl-CoA C-acyltransferase (in reverse):
a short-chain 2-methyl-3-oxoacyl-CoA + coenzyme A→a short-chain 2-methyl fatty acyl-CoA + propanoyl-CoA (EC 2.3.1.16)
PGA1_c12030
PGA1_c22730
PGA1_c33180
PGA1_c03400
PGA1_c34350
PGA1_c04090
PGA1_c04120
Acetyl-CoA C-acyltransferase (in reverse):
a medium-chain 2-methyl-3-oxoacyl-CoA + coenzyme A→a medium-chain 2-methyl fatty acyl-CoA + propanoyl-CoA (EC 2.3.1.16)
PGA1_c12030
PGA1_c22730
PGA1_c33180
PGA1_c03400
PGA1_c34350
PGA1_c04090
PGA1_c04120

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information