MetaCyc Pathway: benzoate biosynthesis III (CoA-dependent, non-β-oxidative) in Phaeobacter inhibens DSM 17395

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Phenylalanine ammonia-lyase:
L-phenylalanine→trans-cinnamate + ammonium
(EC 4.3.1.24; 4.3.1.25; 5.4.3.10)
No genes
trans-cinnamate + ATP + coenzyme A→(E)-cinnamoyl-CoA + AMP + diphosphate
No genes
Enoyl-CoA hydratase (in reverse):
(E)-cinnamoyl-CoA + H2O→(S)-3-hydroxy-3-phenylpropanoyl-CoA
(EC 4.2.1.17)
PGA1_c12020
PGA1_c14440
PGA1_c15660
PGA1_c16990
PGA1_c17350
PGA1_c22740
PGA1_c23460
PGA1_c23920
PGA1_c26820
PGA1_c33450
PGA1_c34200
PGA1_c36500
PGA1_262p01540
PGA1_262p01850
PGA1_262p01980
PGA1_c04110
(S)-3-hydroxy-3-phenylpropanoyl-CoA→benzaldehyde + acetyl-CoA
No genes
Benzaldehyde dehydrogenase (NAD(+)):
benzaldehyde + NAD+ + H2O→benzoate + NADH + 2 H+
(EC 1.2.1.28)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information