MetaCyc Pathway: superpathway of L-cysteine biosynthesis (fungi) in Pedobacter sp. GW460-11-11-14-LB5

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Homoserine O-acetyltransferase:
L-homoserine + acetyl-CoA→O-acetyl-L-homoserine + coenzyme A (EC 2.3.1.31)
CA265_RS08175
O-acetylhomoserine aminocarboxypropyltransferase:
O-acetyl-L-homoserine + hydrogen sulfide→L-homocysteine + acetate + H+ (EC 2.5.1.49)
CA265_RS08180
CA265_RS13080
Cystathionine beta-synthase:
L-homocysteine + L-serine→L-cystathionine + H2O (EC 4.2.1.22)
CA265_RS04375
Cystathionine gamma-synthase:
L-cysteine + O-succinyl-L-homoserine→L-cystathionine + H+ + succinate (EC 2.5.1.48)
CA265_RS08180
CA265_RS08190
CA265_RS13080
Cystathionine gamma-lyase:
L-cystathionine + H2O→L-cysteine + 2-oxobutanoate + ammonium (EC 4.4.1.1)
CA265_RS06375
CA265_RS08190
Cysteine-S-conjugate beta-lyase:
L-cystathionine + H2O→L-homocysteine + ammonium + pyruvate (EC 4.4.1.13)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information