MetaCyc Pathway: pyruvate fermentation to propanoate I in Shewanella loihica PV-4

Add experiment(s):


Methylmalonyl-CoA carboxytransferase:
(S)-methylmalonyl-CoA + pyruvate→oxaloacetate + propanoyl-CoA
(EC 2.1.3.1)
No genes
Malate dehydrogenase (in reverse):
oxaloacetate + NADH + H+→(S)-malate + NAD+
(EC 1.1.1.37; 1.1.1.38)
Shew_0867
Shew_2962
Fumarate hydratase:
(S)-malate→fumarate + H2O
(EC 4.2.1.2)
Shew_0068
Shew_1904
Succinate dehydrogenase (ubiquinone):
fumarate[in] + a menaquinol→succinate[in] + a menaquinone
(EC 1.3.5.1)
Shew_0332
Shew_0333
Shew_0335 (sdhB)
propanoyl-CoA + succinate→succinyl-CoA + propanoate (EC 2.8.3.27)
No genes
Methylmalonyl-CoA mutase (in reverse):
succinyl-CoA→(R)-methylmalonyl-CoA
(EC 5.4.99.2)
No genes
Methylmalonyl-CoA epimerase:
(R)-methylmalonyl-CoA→(S)-methylmalonyl-CoA
(EC 5.1.99.1)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information