MetaCyc Pathway: mycothiol biosynthesis in Mycobacterium tuberculosis H37Rv

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Inositol-3-phosphate synthase:
D-glucopyranose 6-phosphate→1D-myo-inositol 3-monophosphate (EC 5.5.1.4)
Rv0046c
1D-myo-inositol 3-monophosphate + UDP-N-acetyl-α-D-glucosamine→1-O-(2-acetamido-2-deoxy-α-D-glucopyranosyl)-1D-myo-inositol 3-phosphate + H+ + UDP (EC 2.4.1.250)
Rv0486
1-O-(2-acetamido-2-deoxy-α-D-glucopyranosyl)-1D-myo-inositol 3-phosphate + H2O→1-(2-acetamido-2-deoxy-α-D-glucopyranosyl)-1D-myo-inositol + phosphate
No genes
1-(2-acetamido-2-deoxy-α-D-glucopyranosyl)-1D-myo-inositol + H2O→1-(2-amino-2-deoxy-α-D-glucopyranosyl)-1D-myo-inositol + acetate (EC 3.5.1.103)
Rv1170
1-(2-amino-2-deoxy-α-D-glucopyranosyl)-1D-myo-inositol + ATP + L-cysteine→deacetylmycothiol + AMP + diphosphate + H+ (EC 6.3.1.13)
Rv2130c
deacetylmycothiol + acetyl-CoA→mycothiol + coenzyme A + H+ (EC 2.3.1.189)
Rv0819

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information