MetaCyc Pathway: adenosylcobinamide-GDP salvage from cobinamide II in Mycobacterium tuberculosis H37Rv

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Cob(I)yrinic acid a,c-diamide adenosyltransferase:
cob(II)inamide + a [corrinoid adenosyltransferase]→[corrinoid adenosyltranferase]-cob(II)inamide (EC 2.5.1.17)
Rv1314c
Rv2849c
Cob(I)yrinic acid a,c-diamide adenosyltransferase:
2 [corrinoid adenosyltranferase]-cob(II)inamide + a [reduced flavoprotein]→2 [corrinoid adenosyltranferase]-cob(I)inamide + an [oxidized flavoprotein] + 2 H+ (spontaneous) (EC 2.5.1.17)
Rv1314c
Rv2849c
Cob(I)yrinic acid a,c-diamide adenosyltransferase:
2 [corrinoid adenosyltranferase]-cob(I)inamide + 2 ATP + 2 H+→2 adenosylcobinamide + 2 a [corrinoid adenosyltransferase] + 2 triphosphate (EC 2.5.1.17)
Rv1314c
Rv2849c
Adenosylcobinamide hydrolase:
adenosylcobinamide + H2O→adenosylcobyrate + (R)-1-aminopropan-2-ol (EC 3.5.1.90)
No genes
Adenosylcobinamide-phosphate synthase:
adenosylcobyrate + (R)-1-amino-2-propanol O-2-phosphate + ATP→adenosyl-cobinamide phosphate + ADP + H+ + phosphate (EC 6.3.1.10)
Rv2236c
Adenosylcobinamide-phosphate guanylyltransferase:
adenosyl-cobinamide phosphate + GTP + H+→adenosylcobinamide-GDP + diphosphate (EC 2.7.7.62)
Rv0254c

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information