MetaCyc Pathway: isoniazid activation in Mycobacterium tuberculosis H37Rv
| 2 isoniazid + hydrogen peroxide→2 isonicotinate acyl radical + 2 diazene + 2 H2O |
| Rv1908c |
| 2 isonicotinate acyl radical + NAD+ + NADH→2 isonicotinate acyl-NADH adduct + H+ (spontaneous) |
| No genes |
Links:
- Pathway details at MetaCyc
- Fitness data for 1 genes
- All MetaCyc pathways for Mycobacterium tuberculosis H37Rv
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information