| arachidonoyl-CoA + malonyl-CoA + H+→(7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CO2 + coenzyme A |
| No genes |
| (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + NADPH + H+→(3R,7Z,10Z,13Z,16Z)-3-hydroxydocosatetraenoyl-CoA + NADP+ (EC 1.1.1.330) |
| No genes |
| (3R,7Z,10Z,13Z,16Z)-3-hydroxydocosatetraenoyl-CoA→(2E,7Z,10Z,13Z,16Z)-docosa-2,7,10,13,16-pentaenoyl-CoA + H2O (EC 4.2.1.134) |
| No genes |
| (2E,7Z,10Z,13Z,16Z)-docosa-2,7,10,13,16-pentaenoyl-CoA + NADPH + H+→adrenoyl-CoA + NADP+ (EC 1.3.1.93) |
| No genes |
| adrenoyl-CoA + malonyl-CoA + H+→(9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA + CO2 + coenzyme A |
| No genes |
| (9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA + NADPH + H+→(3R,9Z,12Z,15Z,18Z)-3-hydroxytetracosatetraenoyl-CoA + NADP+ (EC 1.1.1.330) |
| No genes |
| (3R,9Z,12Z,15Z,18Z)-3-hydroxytetracosatetraenoyl-CoA→(2E,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + H2O (EC 4.2.1.134) |
| No genes |
| (2E,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + NADPH + H+→(9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + NADP+ (EC 1.3.1.93) |
| No genes |
Linoleoyl-CoA desaturase:
(9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + 2 a ferrocytochrome b5 + dioxygen + 2 H+→(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + 2 a ferricytochrome b5 + 2 H2O (EC 1.14.19.3) |
| Rv3229c |
Acyl-CoA oxidase:
(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + dioxygen→(2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoyl-CoA + hydrogen peroxide (EC 1.3.3.6) |
| No genes |
Enoyl-CoA hydratase (in reverse):
(2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoyl-CoA + H2O→(3S,6Z,9Z,12Z,15Z,18Z)-3-hydroxytetracosapentaenoyl-CoA (EC 4.2.1.17) |
| Rv0130 |
| Rv0222 |
| Rv0456c |
| Rv0632c |
| Rv0673 |
| Rv0675 |
| Rv0860 |
| Rv0905 |
| Rv0971c |
| Rv1070c |
| Rv1071c |
| Rv1136 |
| Rv1141c |
| Rv1142c |
| Rv1472 |
| Rv1935c |
| Rv2486 |
| Rv2679 |
| Rv2831 |
| Rv3039c |
| Rv3373 |
| Rv3374 |
| Rv3516 |
| Rv3550 |
| Rv3774 |
| (3S,6Z,9Z,12Z,15Z,18Z)-3-hydroxytetracosapentaenoyl-CoA + NAD+→(6Z,9Z,12Z,15Z,18Z)-3-oxotetracosapentaenoyl-CoA + NADH + H+ |
| No genes |
Acetyl-CoA C-acyltransferase (in reverse):
(6Z,9Z,12Z,15Z,18Z)-3-oxotetracosapentaenoyl-CoA + coenzyme A→(4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + acetyl-CoA (EC 2.3.1.16) |
| Rv0243 |
| Rv0859 |
| Rv0914c |
| Rv1074c |
| Rv1135A |
| Rv1323 |
| Rv2790c |
| Rv3523 |
| Rv3546 |
| Rv3556c |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information