MetaCyc Pathway: superpathway of pyrimidine nucleobases salvage in Mycobacterium tuberculosis H37Rv

Add experiment(s):


Uracil phosphoribosyltransferase (in reverse):
uracil + 5-phospho-α-D-ribose 1-diphosphate→UMP + diphosphate (EC 2.4.2.9)
Rv1379
Rv3309c
Cytidylate kinase:
UMP + ATP→UDP + ADP (EC 2.7.4.14; 2.7.4.22)
Rv1712
Rv2883c
Nucleoside-diphosphate kinase:
UDP + ATP→UTP + ADP (EC 2.7.4.6)
Rv2445c
CTP synthase:
UTP + ATP + L-glutamine + H2O→CTP + ADP + L-glutamate + 2 H+ + phosphate (EC 6.3.4.2)
Rv1699

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information