| a fatty acid + ATP + coenzyme A→an acyl-CoA + AMP + diphosphate |
| No genes |
Acyl-CoA oxidase:
a 2,3,4-saturated fatty acyl CoA + dioxygen→a (2E)-2-enoyl-CoA + hydrogen peroxide (EC 1.3.3.6) |
| No genes |
Enoyl-CoA hydratase (in reverse):
a (2E)-2-enoyl-CoA + H2O→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA (EC 4.2.1.17) |
| Rv0130 |
| Rv0222 |
| Rv0456c |
| Rv0632c |
| Rv0673 |
| Rv0675 |
| Rv0860 |
| Rv0905 |
| Rv0971c |
| Rv1070c |
| Rv1071c |
| Rv1136 |
| Rv1141c |
| Rv1142c |
| Rv1472 |
| Rv1935c |
| Rv2486 |
| Rv2679 |
| Rv2831 |
| Rv3039c |
| Rv3373 |
| Rv3374 |
| Rv3516 |
| Rv3550 |
| Rv3774 |
3-hydroxyacyl-CoA dehydrogenase:
a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA + NAD+→a 2,3,4-saturated 3-oxoacyl-CoA + NADH + H+ (EC 1.1.1.35) |
| Rv0468 |
| Rv0860 |
| Rv1144 |
| a 2,3,4-saturated 3-oxoacyl-CoA + H2O→a 3-oxoacid + coenzyme A + H+ |
| No genes |
| a 3-oxoacid + H+→a methyl ketone + CO2 (spontaneous) |
| No genes |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information