| a 2,3,4-saturated fatty acid + ATP + coenzyme A→a 2,3,4-saturated fatty acyl CoA + AMP + diphosphate |
| No genes |
Acyl-CoA oxidase:
a 2,3,4-saturated fatty acyl CoA + dioxygen→a (2E)-2-enoyl-CoA + hydrogen peroxide (EC 1.3.3.6) |
| No genes |
Enoyl-CoA hydratase (in reverse):
a (2E)-2-enoyl-CoA + H2O→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA (EC 4.2.1.17) |
| Rv0130 |
| Rv0222 |
| Rv0456c |
| Rv0632c |
| Rv0673 |
| Rv0675 |
| Rv0860 |
| Rv0905 |
| Rv0971c |
| Rv1070c |
| Rv1071c |
| Rv1136 |
| Rv1141c |
| Rv1142c |
| Rv1472 |
| Rv1935c |
| Rv2486 |
| Rv2679 |
| Rv2831 |
| Rv3039c |
| Rv3373 |
| Rv3374 |
| Rv3516 |
| Rv3550 |
| Rv3774 |
3-hydroxyacyl-CoA dehydrogenase:
a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA + NAD+→a 2,3,4-saturated 3-oxoacyl-CoA + NADH + H+ (EC 1.1.1.35) |
| Rv0468 |
| Rv0860 |
| Rv1144 |
Acetyl-CoA C-acyltransferase (in reverse):
a 2,3,4-saturated 3-oxoacyl-CoA + coenzyme A→a 2,3,4-saturated fatty acyl CoA + acetyl-CoA (EC 2.3.1.16) |
| Rv0243 |
| Rv0859 |
| Rv0914c |
| Rv1074c |
| Rv1135A |
| Rv1323 |
| Rv2790c |
| Rv3523 |
| Rv3546 |
| Rv3556c |
Citrate (Si)-synthase:
acetyl-CoA + oxaloacetate + H2O→citrate + coenzyme A + H+ (EC 2.3.3.1; 2.3.3.16; 2.3.3.3) |
| Rv0889c |
| Rv0896 |
| Rv1131 |
Aconitate hydratase:
citrate→cis-aconitate + H2O (EC 4.2.1.3) |
| Rv1475c |
Aconitate hydratase:
cis-aconitate + H2O→D-threo-isocitrate (EC 4.2.1.3) |
| Rv1475c |
Isocitrate lyase:
D-threo-isocitrate→glyoxylate + succinate (EC 4.1.3.1) |
| Rv0467 |
| Rv1915 |
| Rv1916 |
Malate synthase:
acetyl-CoA + glyoxylate + H2O→(S)-malate + coenzyme A + H+ (EC 2.3.3.9) |
| Rv1837c |
Succinate dehydrogenase (ubiquinone):
succinate[in] + an electron-transfer quinone→fumarate[in] + an electron-transfer quinol (EC 1.3.5.1) |
| No genes |
Fumarate hydratase (in reverse):
fumarate + H2O→(S)-malate (EC 4.2.1.2) |
| Rv1098c |
Malate dehydrogenase:
(S)-malate + NAD+→oxaloacetate + NADH + H+ (EC 1.1.1.37; 1.1.1.38) |
| Rv1240 |
| Rv2332 |
Phosphoenolpyruvate carboxykinase (ATP):
oxaloacetate + ATP→phosphoenolpyruvate + ADP + CO2 (EC 4.1.1.49) |
| No genes |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information