MetaCyc Pathway: octane oxidation in Mycobacterium tuberculosis H37Rv

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Rubredoxin--NAD(+) reductase (in reverse):
NADH + 2 an oxidized rubredoxin→2 a reduced rubredoxin + NAD+ + H+ (EC 1.18.1.1)
Rv0688
Alkane 1-monooxygenase:
2 a reduced rubredoxin + octane + dioxygen + 2 H+→octan-1-ol + 2 an oxidized rubredoxin + H2O (EC 1.14.15.3)
Rv0688
Rv3250c
Rv3251c
Rv3252c
octan-1-ol + an oxidized electron carrier→1-octanal + a reduced two electron carrier
No genes
Aldehyde dehydrogenase (NAD(+)):
1-octanal + NAD+ + H2O→NADH + octanoate + 2 H+ (EC 1.2.1.3)
Rv0147
Rv0223c
Rv0458
Rv0768
Rv1731
Rv3293
Butyrate--CoA ligase:
octanoate + ATP + coenzyme A→octanoyl-CoA + AMP + diphosphate (EC 6.2.1.2; 6.2.1.3)
Rv0166
Rv0214
Rv0270
Rv1013
Rv1058
Rv1427c
Rv2187
Rv2505c
Rv3506
Rv3513c
Rv3515c
Rv3561

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information