MetaCyc Pathway: methyl-coenzyme M oxidation to CO2 II in Methanococcus maripaludis JJ

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Tetrahydromethanopterin S-methyltransferase (in reverse):
methyl-CoM[in] + tetrahydromethanopterin[in] + 2 Na+[out]→5-methyltetrahydromethanopterin[in] + coenzyme M[in] + 2 Na+[in]
(EC 2.1.1.86)
MMJJ_RS06300
MMJJ_RS06305
MMJJ_RS06310
MMJJ_RS06315
MMJJ_RS06320
MMJJ_RS06325
MMJJ_RS06330
MMJJ_RS06335
5-methyltetrahydromethanopterin + an oxidized factor 420→5,10-methylene-tetrahydromethanopterin + a reduced factor 420 (EC 1.5.98.2)
MMJJ_RS05145
5,10-methylene-tetrahydromethanopterin + an oxidized factor 420 + H+→5,10-methenyltetrahydromethanopterin + a reduced factor 420 (EC 1.5.98.1)
MMJJ_RS03500
Methenyltetrahydromethanopterin cyclohydrolase:
5,10-methenyltetrahydromethanopterin + H2O→5-formyl-tetrahydromethanopterin + H+
(EC 3.5.4.27)
MMJJ_RS08220
Formylmethanofuran--tetrahydromethanopterin N-formyltransferase (in reverse):
5-formyl-tetrahydromethanopterin + a methanofuran→tetrahydromethanopterin + a formylmethanofuran + H+
(EC 2.3.1.101)
MMJJ_RS06095
a formylmethanofuran + 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O→a methanofuran + CO2 + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster (EC 1.2.7.12)
MMJJ_RS00850
MMJJ_RS05650
MMJJ_RS07925
MMJJ_RS07930
MMJJ_RS07935

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information