MetaCyc Pathway: reductive acetyl coenzyme A pathway II (autotrophic methanogens) in Methanococcus maripaludis JJ

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CO2 + a methanofuran + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster→a formylmethanofuran + 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O (EC 1.2.7.12)
MMJJ_RS00850
MMJJ_RS05650
MMJJ_RS07925
MMJJ_RS07930
MMJJ_RS07935
Formylmethanofuran--tetrahydromethanopterin N-formyltransferase:
a formylmethanofuran + tetrahydromethanopterin + H+→5-formyl-tetrahydromethanopterin + a methanofuran (EC 2.3.1.101)
MMJJ_RS06095
Methenyltetrahydromethanopterin cyclohydrolase (in reverse):
5-formyl-tetrahydromethanopterin + H+→5,10-methenyltetrahydromethanopterin + H2O (EC 3.5.4.27)
MMJJ_RS08220
5,10-methenyltetrahydromethanopterin hydrogenase:
5,10-methenyltetrahydromethanopterin + H2→5,10-methylene-tetrahydromethanopterin + H+ (EC 1.12.98.2)
MMJJ_RS04750
5,10-methylene-tetrahydromethanopterin + a reduced factor 420→5-methyltetrahydromethanopterin + an oxidized factor 420 (EC 1.5.98.2)
MMJJ_RS05145
CO2 + 5-methyltetrahydromethanopterin + coenzyme A + 2 H+ + 2 a reduced ferredoxin [iron-sulfur] cluster→tetrahydromethanopterin + acetyl-CoA + 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O (EC 2.3.3.M4)
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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information