MetaCyc Pathway: chorismate biosynthesis II (archaea) in Methanococcus maripaludis JJ

Add experiment(s):


Aspartate kinase:
L-aspartate + ATP→L-aspartyl-4-phosphate + ADP (EC 2.7.2.4)
MMJJ_RS09120
D-glyceraldehyde 3-phosphate→enolaldehyde + phosphate
MMJJ_RS01455
Aspartate-semialdehyde dehydrogenase (in reverse):
L-aspartyl-4-phosphate + NADPH + H+→L-aspartate 4-semialdehyde + NADP+ + phosphate (EC 1.2.1.11)
MMJJ_RS07195
enolaldehyde→methylglyoxal (spontaneous)
No genes
methylglyoxal + β-D-fructofuranose 1,6-bisphosphate→D-glyceraldehyde 3-phosphate + 6-deoxy-5-ketofructose 1-phosphate (EC 2.2.1.11)
MMJJ_RS03800
6-deoxy-5-ketofructose 1-phosphate + L-aspartate 4-semialdehyde→2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + hydroxypyruvaldehyde phosphate (EC 2.2.1.10)
MMJJ_RS01460
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + NAD+ + H2O→3-dehydroquinate + ammonium + NADH + H+ (EC 1.4.1.24)
MMJJ_RS05430
3-dehydroquinate dehydratase:
3-dehydroquinate→3-dehydroshikimate + H2O (EC 4.2.1.10)
MMJJ_RS03190
MMJJ_RS07180
Shikimate dehydrogenase (in reverse):
3-dehydroshikimate + NADPH + H+→shikimate + NADP+ (EC 1.1.1.25)
MMJJ_RS00280
Shikimate kinase:
shikimate + ATP→shikimate 3-phosphate + ADP + H+ (EC 2.7.1.71)
MMJJ_RS03665
3-phosphoshikimate 1-carboxyvinyltransferase:
shikimate 3-phosphate + phosphoenolpyruvate→5-enolpyruvoyl-shikimate 3-phosphate + phosphate (EC 2.5.1.19)
MMJJ_RS08145
Chorismate synthase:
5-enolpyruvoyl-shikimate 3-phosphate→chorismate + phosphate (EC 4.2.3.5)
MMJJ_RS07475

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information