MetaCyc Pathway: superpathway of pyrimidine deoxyribonucleoside salvage in Marinobacter adhaerens HP15

Add experiment(s):


Cytidine deaminase:
2'-deoxycytidine + H+ + H2O→2'-deoxyuridine + ammonium (EC 3.5.4.5)
No genes
Deoxycytidine kinase:
2'-deoxycytidine + a nucleoside triphosphate→dCMP + a nucleoside diphosphate + H+ (EC 2.7.1.74)
No genes
Deoxynucleoside kinase:
2'-deoxyuridine + ATP→dUMP + ADP + H+ (EC 2.7.1.145; 2.7.1.21)
No genes
(Deoxy)nucleoside-phosphate kinase:
dCMP + ATP→dCDP + ADP (EC 2.7.4.13; 2.7.4.14; 2.7.4.25)
HP15_1365
Thymidylate synthase:
dUMP + a 5,10-methylenetetrahydrofolate→dTMP + a 7,8-dihydrofolate (EC 2.1.1.45)
HP15_586
Nucleoside-diphosphate kinase:
dCDP + ATP→dCTP + ADP (EC 2.7.4.6)
HP15_1489
HP15_797
Deoxynucleoside kinase:
thymidine + ATP→dTMP + ADP + H+ (EC 2.7.1.145; 2.7.1.21)
No genes
T(2)-induced deoxynucleotide kinase:
dTMP + ATP→dTDP + ADP (EC 2.7.4.12; 2.7.4.13; 2.7.4.9)
HP15_2207
HP15_4160
Nucleoside-diphosphate kinase:
dTDP + ATP→dTTP + ADP (EC 2.7.4.6)
HP15_1489
HP15_797

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information