MetaCyc Pathway: benzoate biosynthesis III (CoA-dependent, non-β-oxidative) in Marinobacter adhaerens HP15

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Phenylalanine ammonia-lyase:
L-phenylalanine→trans-cinnamate + ammonium
(EC 4.3.1.24; 4.3.1.25; 5.4.3.10)
No genes
trans-cinnamate + ATP + coenzyme A→(E)-cinnamoyl-CoA + AMP + diphosphate
No genes
Enoyl-CoA hydratase (in reverse):
(E)-cinnamoyl-CoA + H2O→(S)-3-hydroxy-3-phenylpropanoyl-CoA
(EC 4.2.1.17)
HP15_1141
HP15_12
HP15_1232
HP15_1512
HP15_1737
HP15_1740
HP15_2575
HP15_2692
HP15_2717
HP15_3410
HP15_3941
HP15_4082
HP15_4094
HP15_55
HP15_864
HP15_908
HP15_909
(S)-3-hydroxy-3-phenylpropanoyl-CoA→benzaldehyde + acetyl-CoA
No genes
Benzaldehyde dehydrogenase (NAD(+)):
benzaldehyde + NAD+ + H2O→benzoate + NADH + 2 H+
(EC 1.2.1.28)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information