MetaCyc Pathway: benzoate biosynthesis I (CoA-dependent, β-oxidative) in Marinobacter adhaerens HP15

Add experiment(s):


Phenylalanine ammonia-lyase:
L-phenylalanine→trans-cinnamate + ammonium (EC 4.3.1.24; 4.3.1.25; 5.4.3.10)
No genes
trans-cinnamate + ATP + coenzyme A→(E)-cinnamoyl-CoA + AMP + diphosphate
No genes
Enoyl-CoA hydratase (in reverse):
(E)-cinnamoyl-CoA + H2O→(S)-3-hydroxy-3-phenylpropanoyl-CoA (EC 4.2.1.17)
HP15_1141
HP15_12
HP15_1232
HP15_1512
HP15_1737
HP15_1740
HP15_2575
HP15_2692
HP15_2717
HP15_3410
HP15_3941
HP15_4082
HP15_4094
HP15_55
HP15_864
HP15_908
HP15_909
3-hydroxyacyl-CoA dehydrogenase:
(S)-3-hydroxy-3-phenylpropanoyl-CoA + NAD+→3-oxo-3-phenylpropanoyl-CoA + NADH + H+ (EC 1.1.1.35)
HP15_1232
HP15_1512
HP15_3941
HP15_48
Acetyl-CoA C-acyltransferase (in reverse):
3-oxo-3-phenylpropanoyl-CoA + coenzyme A→benzoyl-CoA + acetyl-CoA (EC 2.3.1.16)
HP15_1009
HP15_1233
HP15_1513
HP15_2344
HP15_2423
HP15_2695
HP15_2996
HP15_35
HP15_3943
HP15_49
HP15_5
benzoyl-CoA + H2O→benzoate + coenzyme A + H+
No genes
Benzoate--CoA ligase:
benzoate + ATP + coenzyme A→benzoyl-CoA + AMP + diphosphate (EC 6.2.1.25)
No genes
benzoyl-CoA + benzyl alcohol→benzyl benzoate + coenzyme A (EC 2.3.1.196)
No genes
benzyl benzoate + H2O→benzoate + benzyl alcohol + H+
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information