MetaCyc Pathway: mixed acid fermentation in Marinobacter adhaerens HP15

Add experiment(s):


Phosphoenolpyruvate carboxylase (in reverse):
phosphoenolpyruvate + hydrogen carbonate→oxaloacetate + phosphate
(EC 4.1.1.31)
HP15_795
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP
(EC 2.7.1.40)
HP15_2176
D-lactate dehydrogenase (in reverse):
pyruvate + NADH + H+→(R)-lactate + NAD+
(EC 1.1.1.28)
No genes
Malate dehydrogenase (in reverse):
oxaloacetate + NADH + H+→(S)-malate + NAD+
(EC 1.1.1.37; 1.1.1.38)
No genes
Formate C-acetyltransferase (in reverse):
pyruvate + coenzyme A→acetyl-CoA + formate
(EC 2.3.1.54)
No genes
Acetaldehyde dehydrogenase (acetylating) (in reverse):
acetyl-CoA + NADH + H+→acetaldehyde + coenzyme A + NAD+
(EC 1.2.1.10)
HP15_1114
HP15_3135
HP15_4035
Citrate (Si)-synthase:
acetyl-CoA + oxaloacetate + H2O→citrate + coenzyme A + H+
(EC 2.3.3.1; 2.3.3.16; 2.3.3.3)
HP15_1516
formate + H+→CO2 + H2
No genes
Fumarate hydratase:
(S)-malate→fumarate + H2O
(EC 4.2.1.2)
HP15_1143
HP15_3132
Phosphate acetyltransferase:
acetyl-CoA + phosphate→acetyl phosphate + coenzyme A
(EC 2.3.1.8)
HP15_1498
Acetate kinase (in reverse):
acetyl phosphate + ADP→acetate + ATP
(EC 2.7.2.1; 2.7.2.15)
HP15_1245
HP15_1499
Aconitate hydratase:
citrate→cis-aconitate + H2O
(EC 4.2.1.3)
HP15_1930
HP15_2203
HP15_3433
Alcohol dehydrogenase (in reverse):
acetaldehyde + NADH + H+→ethanol + NAD+
(EC 1.1.1.1)
HP15_1034
HP15_1388
HP15_1797
HP15_2019
HP15_3135
HP15_3142
HP15_3944
HP15_4017
HP15_921
Succinate dehydrogenase (ubiquinone):
fumarate[in] + a menaquinol→succinate[in] + a menaquinone
(EC 1.3.5.1)
No genes
Aconitate hydratase:
cis-aconitate + H2O→D-threo-isocitrate
(EC 4.2.1.3)
HP15_1930
HP15_2203
HP15_3433
Isocitrate dehydrogenase (NADP(+)):
D-threo-isocitrate + NADP+→CO2 + 2-oxoglutarate + NADPH
(EC 1.1.1.42)
HP15_1636
HP15_3800

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information