MetaCyc Pathway: ureide biosynthesis in Shewanella oneidensis MR-1

Add experiment(s):


IMP dehydrogenase:
IMP + NAD+ + H2O→XMP + NADH + H+
(EC 1.1.1.205)
SO0805
SO3293 (guaB)
5'-nucleotidase:
XMP + H2O→xanthosine + phosphate
(EC 3.1.3.5)
SO0372
SO2001 (ushA)
SO2484
SO3317
SO3435 (surE)
Purine-nucleoside phosphorylase:
xanthosine + phosphate→xanthine + α-D-ribose-1-phosphate
(EC 2.4.2.1)
SO0092 (deoD-1)
SO1221 (deoD-2)
SO2719 (deoD-3)
SO4297
SO4467
Xanthine dehydrogenase:
xanthine + NAD+ + H2O→urate + NADH + H+
(EC 1.17.1.4)
No genes
Urate oxidase:
urate + dioxygen + H2O→(S)-5-hydroxyisourate + hydrogen peroxide
(EC 1.7.3.3)
No genes
Hydroxyisourate hydrolase:
(S)-5-hydroxyisourate + H2O→(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+
(EC 3.5.2.17)
No genes
(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+→(S)-(+)-allantoin + CO2 (EC 4.1.1.97)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information